Ho tloha ts'ebetsong ea lithibela-pelehi tsa molomo tsa basali ka bo-1950 ho fihlela tsoalo ea lesea la test tube ka bo-1970 le ho etsoa ka katleho ha linku tsa Dolly ho elella bofelong ba lilemo tsa bo-1990, thekenoloji ea meriana ea ho ikatisa e entse tsoelo-pele e kholo theknoloji ea Human assisted reproductive (Art) haholo-holo theknoloji e khethehileng. ho thusa bakuli bao ba ntseng ba sa khone ho emola ka mor'a phekolo ea kamehla ho kopanya mahe le peō ea botona ka maiketsetso tlas'a maemo a laboratori ho finyella bokhachane.Kaha theknoloji ena e arola ka ho feletseng thobalano le tsoalo, tsoelo-pele ea eona e potlakileng e boetse e tlisitse letoto la mathata a boitšoaro, a molao le a sechaba, a etsa hore tsoelo-pele ea bonono e fapane haholo le litloaelo tse ling tsa bongaka, e be moriana o hōlang ka likhang.
Infertility ke lefu la tsamaiso ea ho ba le bana le khetholloang ka ho hlōleha ho ima ka mor'a likhoeli tse 12 kapa ho feta tsa thobalano e tloaelehileng ntle le lithibela-pelehi.Ho ata ha lefats'e la ho hloka thari ho eketsehile ho tloha ho 11% ka 1997 ho ea ho 15.4% ka 2018, 'me ho lebeletsoe ho eketseha ho 17.2% ka 2023. Ho ata ha ho hloka thari United States ho lebeletsoe ho eketseha ho tloha 16% ka 2018 ho ea ho 17.9% ka 2023, ha ts'ebetso ea ho hloka thari Chaena e lebelletsoe ho eketseha ho tloha ho 16.0% ka 2018 ho isa ho 18.2% ka 2023.
